Scientific Associate Director - Project Toxicologist

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientific Associate Director - Project Toxicologist

What you will do

Let’s do this. Let’s change the world. In this vital role, you will be the key scientific interface between TS&BA and your project teams from discovery through post-marketing. The Translational Safety & Bioanalytical Sciences (TS&BA) function at Amgen is seeking a Scientific Associate Director to serve as a Project Toxicologist and a Subject Matter Expert, reporting to the Senior Director Head Therapeutic Area Strategy Leaders and Business Development Liaisons.

You will develop and implement a fit-for-purpose nonclinical safety strategy based on a strong scientific foundation, flexibly evolve the strategy in response to team goals and emerging data and lead multidisciplinary TS&BA teams. As a project team representative (PTR), you will partner with project teams developing therapeutics leveraging a variety of modalities (including biotherapeutics, small molecules and RNA therapies) to treat diseases in inflammation, oncology and/or cardiometabolic diseases, including obesity and rare diseases. There is potential for opportunities with broader Inflammation Therapeutic Area responsibilities as well. PTRs are encouraged to develop subject matter expertise related to a specific modality, therapeutic area, or safety concern.

The successful candidate will have:

• A track record of scientific leadership in drug development (including IND/CTA filings) as well as in nonclinical development with a strong understanding of cross-functional needs and the ability to develop integrated plans to enable successful development of a therapeutic.
• Experience with matrix management and demonstrated effective mentoring skills.
• Presented nonclinical safety issues at regional, national and/or international regulatory meetings and participated in external industry initiatives to improve drug safety assessment paradigms.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional we seek is a [type of person] with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 4 years of Toxicology experience

Or

Master’s degree and 7 years of Toxicology experience

Or

Bachelor’s degree and 9 years of Toxicology experience

Preferred Qualifications:

• A minimum of 8 years of drug development experience, at all stages of development including late-stage assets and interactions with global regulatory agencies for IND/CTA and NDA/BLA filings
• Expertise in the field of immunology, either through immune-toxicology, immune-oncology or immunology related drug target support.
• End-to-end small and large molecule safety assessment experience across multiple therapeutic areas and modalities potentially including antibody drug conjugates and T-cell engagers
• External visibility as a toxicology expert as demonstrated by an external presentation and publication record and/or leadership or participation of external collaborative groups
• Experience supporting business development efforts in the conduct of due diligence evaluations as translational safety team member
• Comfortable operating as a cross-functional and inter-functional thought partner on multi-disciplinary teams across R&D functions
• Experienced scientific leader with direct or matrixed management experience
• Diplomate of the American Board of Toxicology
• Excellent and professional communicator; proven ability to influence a broad spectrum of partners toward achieving business goals

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen anticipates accepting applications until 5/7/25; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range