Overview
The Director of Health Economics and Outcomes Research (HEOR) is responsible for developing a global strategy for generating evidence, supporting submissions for health technology assessments worldwide, and conducting health economics analyses and real-world evidence studies. This role will serve as the internal expert on health economics for both the US and global markets. In this role, they are expected to have a strong understanding of how HEOR evidence can demonstrate the value of our cell therapy to payers and financial stakeholders worldwide. Previous experience in oncology or rare diseases is essential, and experience in cell therapy is highly desirable. They will also possess both deep technical expertise and a willingness to delve into models and data, as well as the experience and skills to drive strategy and collaborate closely with leadership and senior cross-functional stakeholders.
Essential Functions and Responsibilities
- Develop and execute the HEOR strategy, ensuring alignment with market access, regulatory, and clinical objectives
- Design, develop, and manage health economic models, including cost-effectiveness analyses and budget impact models
- Collaborate with internal stakeholders to identify evidence that will support product value and conduct real-world evidence studies to demonstrate the clinical and economic value of oncology therapies
- Manage quality-of-life (QoL) data for all clinical trials, including conducting quality checks and analysis on QoL data as required for HTA submissions
- Oversee the preparation of HEOR-related documents, including dossiers, payer presentations, and publication of research findings
- Lead and participate in interactions with external stakeholders such as health economics, payers, and key opinion leaders
- Stay abreast of industry trends, policies, and regulatory requirements related to HEOR
- Communicate HEOR updates, recommendations, and analysis regularly to the broader Iovance organization, including to senior leadership
- Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
- Perform miscellaneous duties as assigned.
Travel – 20%
Required Education, Skills, and Knowledge
- 12+ years of related experience in biopharmaceutical industry with extensive experience in health economics and outcomes research
- Advanced degree in health economics, epidemiology, biological sciences, or related.
- 5+ years of prior leadership experience, with proven people management skills
- Strong interpersonal, collaborative, and relationship-building skills.
- Demonstrated strategic thinking skills, strong business acumen, and excellent process and management skills.
- Superior strategic and tactical planning within a pharmaceutical environment is necessary.
- Experience in submitting Health Technology Assessments in the EU
- Experience developing and aligning global pricing bands with senior management
- Cell therapy experience preferred, or otherwise oncology / rare disease experience
- Extensive knowledge of publicly available scientific literature, modeling assumptions, and reviews/appraisals of recent dossiers for high-cost drugs in major markets
- Experience modeling synthetic comparator arms to support ex-US dossiers based on single-arm trials
- Track record of successfully managing high-performing teams and delivering excellence
- Proven experience in developing and executing economic models and real-world evidence studies
- Deep technical understanding of HEOR modeling methodologies
- Extensive experience with developing dossiers to support health technology assessment submissions in multiple markets
- Excellent written and oral communication skills
- Proficient in presenting, with significant expertise in delivering presentations at the executive level
Preferred Education, Skills, and Knowledge
- PhD in health economics, epidemiology, biological sciences preferred
The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodation may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request accommodation.
Physical Demands and Activities Required
- Must be able to remain stationary, standing or sitting for prolonged periods.
- Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects.
- Must have visual acuity to prepare and analyze data and figures, view a computer screen, and read extensively.
- This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers.
- Must be able to communicate with others to exchange information.
Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines
Work Environment
This job operates in a professional workplace or remote office environment and requires standard office equipment and keyboards. Employees who work remotely are expected to maintain their workspace and environment safely and free from safety hazards.
The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or change the position's responsibilities at any time.
Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com.
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