Sr Director, Bioinformatics R&D

The mission of the Innovation Lab is to increase the diagnostic yield of our exome and genome products and reduce the time to diagnosis for patients with undiagnosed hereditary disease. Our vision is to deliver personalized and actionable health insights to every person who orders a genetic test from GeneDx. Achievement of our goals will require a culture of innovation, where creativity, experimentation, and the pursuit of new ideas are encouraged and embraced. Individuals are empowered to think critically, take risks, and challenge the status quo, to generate breakthrough solutions and drive positive change.

Summary:

We are seeking a highly motivated, collaborative, and adaptable Sr Director, Bioinformatics R&D to lead strategy and execution of advanced bioinformatics pipeline development, a core component of our diagnostic platform. The ideal candidate will bring scientific leadership, prior industry experience, and proficiency working with high-dimensional, multi-modal datasets. The role will include building and transforming our bioinformatics capabilities while working with our scientific team, collaborating with external sequencing partners, and ultimately establishing bioinformatics as a key pillar for diagnosing rare disease.

Responsibilities:

• Grow and direct a team in order to develop infrastructure and new algorithms for analyzing DNA, RNA and proteomic data. 
• Formulate and implement strategic plans for bioinformatics solutions to meet immediate and future business objectives.
• Oversee planning, designing, development, and implementation of bioinformatics infrastructure, including data, hardware, software components, and system integration.
• Collaborate with internal teams to drive programs from the Innovation Lab into production use. 
• Develop and deploy novel bioinformatics analyses and tools and monitor emerging technologies.
• Work closely with cross-functional teams, including researchers from various fields to design experiments and develop research questions.
• Contribute to monthly executive team meetings with strategic proposals for accelerating bioinformatics improvements, roadmaps for transforming existing capabilities, and status reports for ongoing bioinformatics R&D projects.
• Design and develop guidelines and processes to ensure high levels of quality and efficiency for genetic testing and rare disease diagnostics.
• Ensure regulatory compliance for bioinformatics technology development and operations.
• Provide advice, guidance, and mentoring to bioinformatics staff.

People Manager:

• Yes

Education, Experience, and Skills:

• Advanced degree (Ph.D. preferred) in Bioinformatics, Computational Biology, or a related field
• Extensive experience in bioinformatics, with a strong background in computational analysis and tool development
• Proficiency in programming languages (e.g., Python, R) and bioinformatics software
• Proven ability to lead and manage bioinformatics teams and/or projects
• Excellent communication skills for interacting with stakeholders and presenting findings

Physical Demands: 

• Ability to stand, walk, and sit for extended periods.

Work Environment:

• Fully remote.